Pathologists are perfectly positioned to lead a data-driven revolution that will bring health systems firmly into the 21st century, transforming patient outcomes globally via world-class interoperable diagnostics and data workflows. Using data-rich laboratory information management systems (LIMS), pathologists can reshape healthcare with patients firmly at the centre of models of care. Innovative diagnosticians are collaborating with clinicians beyond traditional organisational silos throughout labs, hospitals, and trusts to deliver a higher quality of care that is increasingly integrated and multidisciplinary.